Alphabet training of primary school students is an essential, but challenging activity. Alphabet knowledge is an important fundamental literacy skill which has been found to directly impact the future academic success of students. Game-based learning and the use of multimodal engagement activities have been found to be effective intervention strategies in successful alphabet training programmes. In this study, a Kinect based digital Catcher Game was developed for English alphabet training of primary school students. For a duration of 4 weeks, a control group (CG) consisting of 41 Class-III students received traditional classroom training for 60 min each day. During the same period, an intervention group (IG) consisting of 45 Class-III students was trained for 30 min in the traditional class and using a Catcher Game session for another 30 min. The alphabet knowledge performances of the two groups were compared before and after the game-based training intervention. During the pre-test, no statistically significant differences were observed in the alphabet knowledge performance of the CG and IG. In the post-intervention evaluation, the IG students were found to perform significantly better in the test than the CG. During their post-intervention feedback, most of the IG students and teachers talked favorably about the use of Catcher Game intervention and attributed the significant improvement in IG performance to this intervention. Post-intervention, the teachers also reported a significant improvement in the motivation and engagement among the IG students during regular classroom sessions.