Virtual reality (VR) technology has shown great potential on intervention of social skills for children with autism spectrum disorder (ASD). This review aimed to review the application of VR in current social skills intervention targeting autistic children and evaluate its effect. After searching and screening three databases, we found 20 papers on interventions for children with ASD using VR technology, including three studies of social communication, six studies about social-emotional reciprocity, nine studies on social interaction, and eight studies of on social cognition. First, concerning the age of the children involved in the interventions, we found that VR devices were more suitable for children with ASD who were older. Second, regarding VR devices, we recommend laptop VR devices based on the cost, non-invasiveness, and effectiveness of their use in interventions. The VR application form of game is more advisable. More importantly, for the design of the VR intervention, based on the adoption article, we found that using a single participant worked better. This research presents the overall effects and limitations of this literature as well as implications for future work.