Work placement is an important aspect of higher education studies and career preparation. Effective preparation is crucial for students to succeed in placements, yet little is known about international students' placement preparation, particularly regarding their sensemaking. This qualitative study, guided by an integrative theoretical framework, examined international health science (HSc) undergraduate students' sensemaking behaviors as they prepare for in-person placements in a host country. Data were gathered through 36 semi-structured interviews with 12 international HSc undergraduate students (three with each student). Findings unravel complicated psychological and interpersonal processes undergone by student participants during pre-placement sensemaking. These insights can inform institutional strategies to support international students in building sensemaking capacities to effectively prepare for placements and post-study work transitions.