This study was conducted in Islamabad Capital Territory of Pakistan to explore possible strategies for improved professional development of Prospective Teachers (PTs). Primary purpose was to propose a conceptual framework for ensuring university-school partnership as existing literature indicated that such partnership can offer unique opportunities to improve the level of professional development activities for PTs. Teacher educators and school principals constituted the population of the study. Collected data reflected that for improving the quality of teaching practice, there is a dire need to ensure an operative connection among teacher educators, school principals, cooperative teachers, and prospective teachers. Themes generated from data (collected from teacher educators and school principals) were utilised to develop a tentative conceptual framework for university-school partnership. Afterward, focus group discussions were arranged with educational experts for validation purposes, and by incorporating the suggestions of experts, the final draft of the university-school partnership framework was developed.