Microaggressions are a form of subtle violence that young gay men experience throughout their lives, which are known for negatively affecting mental health. A qualitative study with focus groups and in-depth interviews was conducted with 26 young gay men from three geographic areas of Mexico to explore their experiences of microaggressions based on sexual orientation and their impact on mental health. Results showed that microaggressions are present in all stages of life, mainly with family, friends, school, and in public and private spaces, and have behavioral, cognitive, and emotional effects such as sadness, shame, fear, crying, and concealment. The experience of these events and their consequences continue throughout all stages of life. The results suggest the importance of creating inclusive contexts within family and educational environments where gay youth can develop free of discrimination, especially in childhood and adolescence.