This study presents the findings of a systematic review of empirical research on the use of augmented reality (AR), virtual reality (VR), mixed reality (MR), and extended reality (XR) to present social skill instruction to school-age students with autism spectrum disorder (ASD). Forty-one articles met the inclusion criteria. Studies targeted relationship skills, emotion recognition, social awareness, cooperation, and executive functioning. The intervention caused statistical improvement in 15 of the 41 studies (37%). Practitioners, parents, and researchers reported significant improvement of social skills in 32 studies (83%). We suggest modifications to the technology and interventions within the technology which may increase statistical gains for students. We conclude with recommendations for researchers and practitioners implementing AR and VR delivered social skill interventions.