Individuals with autism spectrum disorder (ASD) often experience learning challenges that impact their ability to navigate the social and vocational world of adults without disabilities. Lack of independent functioning correlates with poor postschool outcomes for many individuals with ASD. In order to improve social and vocational outcomes, instruction must focus on teaching personal care skills. Personal care skills (i.e., grooming/hygiene, dressing, eating) represent a foundational set of skills needed for individuals with ASD to achieve independence and improve quality of life. The present literature review examines and summarizes interventions to teach personal care skills to individuals with ASD. The interventions fall into four categories based on intervention components: (a) video-based instruction, (b) behavioral in vivo procedures, (c) audio cuing, and (d) social stories. The results of the reviewed studies indicated improved performance for all participants across intervention categories for a variety of personal care skills. Additional discussion includes limitations and suggestions for future research.