Leaders with ever-evolving learning agility demonstrate high performance by making quick and better decisions in the face of uncertain situations. This study aimed to determine the relationship between school principals' learning agility and decision-making styles and the moderating role of gender in this relationship. The research is carried out according to the relational survey model. SPSS Process Macro software was used to examine the regulatory role. The study group for the research consists of 383 school principals and vice principals working in Istanbul. According to the findings, the highest correlation was found between learning agility and rational decision-making style. Again, the results of the research concluded that learning agility has a positive effect with an intuitive, dependent decision-making style and a negative effect with an avoidant decision-making style. In addition, the moderating role of gender was determined between learning agility and avoidant decision-making style.