The aim of the study is to examine whether job satisfaction mediates and strengthens the relationship between administrative empowerment and organizational commitment among academic staff in Higher Education - Palestinian universities. A questionnaire was implemented during the data collection process. The study sample consisted of academic staff in Higher Education. Two hundred eighty-seven academic staff from seven different universities participated in the study. Data analysis involved calculating descriptive statistics, t-test, (ANOVA) test, correlation, and regression analysis. The results of the study indicated that administrative empowerment, Organizational commitment, and job satisfaction were statistically significant; moreover, it was found that administrative empowerment through job satisfaction impacts Organizational commitment. Management of universities should appreciate these results as good empowerment practices can increase employee job satisfaction. The current study model that has been developed provides that administrative empowerment through job satisfaction helps universities positively influence the organizational commitment of academic staff in universities.