Using a sample of 1031 students from a public university, who responded to the NSSE survey in the Spring of 2018, this study explored the relationships between high-impact practices (HIPs) and several student academic performance metrics. Student responses to the NSSE HIPs participation questions were combined with their academic performance (GPA, credit hour completion, years-to-degree). Linear regression results show that the number of HIPS is a significant predictor of all academic performance metrics. The study also found significant differences between student populations and across course delivery modes regarding their participation in HIPs.