E-learning presents a significant opportunity for developing countries to rapidly increase the availability of higher education to their population. However, e-learning is not widely adopted in many developing countries such as Nigeria. This study aims to advance our understanding of the determinants of e-learning adoption by examining the factors influencing e-learning adoption intentions among academic staff in higher education institutions in Nigeria. Applying the decomposed theory of planned behavior and using sample data collected from 188 respondents, the findings of the study demonstrate that e-learning beliefs are significant factors that indirectly influence e-learning adoption. This study extends our understanding of the determinants of e-learning adoption and provides valuable cues to managers of higher education institutions that will aid their e-learning adoption efforts.