The use of online courses has expanded dramatically at institutions of higher education over the last several decades. Appropriate design of an online course is instrumental in determining the quality of the student experience and the amount of material students retain from the class. However, the instructor has a tremendous amount of freedom when it comes to course design. This paper contains the lessons learned from teaching face-to-face and online Principles of Microeconomics and Principles of Macroeconomics courses for twenty years. Topics discussed include general considerations such as overall course design and the appropriate vehicle for communicating the course information as well as specific design decisions such as grouping of material within the course, video design, assignment design, accessibility issues, and testing procedures.