Purpose: The purpose of this study is to investigate university-industry partnerships in Armenia from the viewpoint of universities. By doing so, it contributes to the existing literature on university-industry collaboration by identifying and addressing the specific challenges that impede the establishment of successful university-industry partnerships in Armenia and other post-Soviet countries. Design/methodology/approach: A comprehensive literature review was conducted to examine the barriers, benefits and institutional, functional framework of collaboration. Additionally, this study used a survey methodology to gather data from faculty managing staff members at six Armenian higher educational institutions on various aspects of university-industry collaboration as well as the perceptions and experiences of the participants. Findings: The results show that the effectiveness and applicability of the university-industry collaboration channels and institutional structures in six higher educational institutions are limited. Specifically, the channels that rely on academic entrepreneurship and innovation were found to be currently unviable. Moreover, the existence of spin-offs and start-ups is notably absent. Furthermore, limited access to funding and inadequate entrepreneurial support systems pose significant barriers to developing university-industry partnerships in Armenian reality. Originality/value: This study represents a pioneering effort within the context of Armenian higher educational institutions, as it is the first time a survey has been organized to specifically investigate the topic of university-industry partnerships. Before this study, there was a lack of empirical research and data collection on this topic in Armenian higher education settings. Therefore, this research holds significant originality and contributes to filling the existing gap in knowledge regarding university-industry partnerships in Armenia. The research is shedding light on a previously unexplored area and providing a valuable contribution to the field of university-industry collaboration research in Armenia and other post-Soviet countries.