This study explores factors influencing school adjustment in immigrant students in Catalonia, Spain. Low school adjustment levels can lead to failure or dropout, particularly among immigrant students. The research analyzes acculturation strategies, intergroup contact, perceived discrimination, and origin's impact on school adjustment. Students from African, Latin American, and European backgrounds completed a questionnaire, revealing four acculturation strategies: marginalization, assimilation to Catalan culture, integration, and assimilation to Catalan and Spanish cultures. A k-means cluster analysis identified these patterns. Linear regression highlighted intergroup contact, integration vs. marginalization, and integration vs. assimilation to Catalan culture as significant predictors. Higher intergroup contact scores correlated with improved school adjustment, while adopting integration or assimilation to Catalan culture predicted better adjustment compared to marginalization. Understanding and addressing these factors is vital for enhancing immigrant students' educational experiences and reducing the risk of academic challenges.