The outcome of a psychodynamic counselling intervention for students seeking psychological help at a university counselling centre in Italy was evaluated by examining its effect on clinical symptoms of the students. The intervention consisted of four counselling sessions and a later three-month follow-up session. The sample (N = 160) was drawn from a population of 360 university students. An in-treatment group (n = 86) was compared to a waiting-list comparison group (n = 74). Post-test measures were administered one month after baseline for each group. The psychodynamic counselling intervention was found to be a valid method to reduce psychopathological symptoms and to improve psychological adjustment among university students.