Repeated closures of the world's science museums to stem the spread of COVID-19 have significantly reduced visitors' access to informal science learning opportunities. Interviews with educators and an analysis of the online content of a science museum were used in this case study to examine the impact of this phenomenon on informal science education. We present several education examples to highlight how educators have attempted to adapt. Specifically, we describe and characterize educators' strategies--"collaboration, networking," and "feedback"--to address difficulties involved in developing virtually accessible content that will engage users. In addition, we analyze essential attributes of informal learning in the science museum attributes of "interaction, free-choice learning, hands-on experience," and "authentic learning" that the educators kept in mind while planning and redesigning educational programs and cultural events in response to COVID-19. We conclude by forecasting the future of science museums based on the educators' perceptions of their roles and the nature of informal science learning, assuming that educators are the crucial agents to build a new future direction.