This research aims at empowering teachers' learning to develop innovative skills for students at high schools under the Office of the Basic Education Commission. It is one of the research projects in the research series regarding 21st century skills which are the outcomes of the advancement of digital technology as well as society becoming knowledge-based in the 21st century by processing many different views which have been proposed globally across the Internet and sorting them to create educational innovation. The objective of the research and development methodology is to develop an individual which will then lead to the development of the work; provided that a person who has knowledge is then encouraged to put it in action, it will supposedly result in more efficient work according to the concept of "knowledge + action = power". This concept itself has led to the study's idea of "empowering teachers' learning and applying the results in their teaching". Therefore, the result of the study is an educational innovation called "online self-training program to empower teachers' learning in order to develop students' innovative skills" which has been approved of its quality by the stakeholder teachers who have used this educational innovation and approved through experimental field research which was efficient as hypothesized in the research. As a result, this online self-training program can be publicly disseminated to develop the teachers to afterwards develop their students in high schools under the Office of the Basic Education Commission who were primarily the target group of this study across the country.