The purpose of this study was to explore Swedish natural science sexuality education as a material-discursive practice. More specifically, we sought to investigate ways in which the phenomenon of "oskuld," which in Swedish means sexual innocence or to be without guilt, comes into being among 17-18-year-old students. The study, conducted in two upper secondary school classes for eight and six weeks respectively, involved in total 53 participating students. Field notes and audio-recordings were used in data construction. With a grounding in Baradian theory we explore how space, time and matter--spacetimematter--intra-actively enact notions of virginity within students' conversations. Findings show that a physiological knowledge base as well as the opportunity for students to encounter their own notions are crucial in overcoming the reproduction of norms related to the phenomenon of virginity.