During recent decades, educational reform in the U.S. has favored standards-driven curricula with the purpose of improving education. However, national assessments have not demonstrated significant improvements in educational outcomes, especially among economically disadvantaged and minoritized populations. To mitigate these outcomes, youth-serving organizations provide children from these populations with out-of-school time programs to enhance their academic and social skills. This study highlights the significance of programs offered by nonprofit organizations like the Boys & Girls Clubs and the need to establish partnerships with universities to foster systematic collaboration. The program described in this article is a one-week summer science camp for students entering grades 4-7. The authors created an instructional unit that integrated literacy and mathematics into a science unit focused on water quality and related environmental issues, while also exploring student outcomes. The interdisciplinary project-based instructional unit focused on culturally responsive practices. Through these practices, students developed awareness of environmental issues and increased their understanding and use of scientific vocabulary related to water quality.