The purpose of the study is to identify the Sense of responsibility of science teachers towards the learning of their students from the perspective of the teachers themselves; the study has included three domains (cognitive, skillful, and emotional); and to demonstrate the differences in the level of responsibility among science teachers based on gender, rank, and educational qualification. The study's sample consists of (123) teachers from the Salt Region's Directorate of Education. The research instrument includes (28) items whose validity and reliability is verified. The results reveal that there is no statistical significant difference in the sense of responsibility among teachers based on their gender or their rank. However, the results reveal that teachers with an educational qualification had a greater sense of responsibility than their peers who lack such a qualification.