Caregiver-mediated interventions have been used to address social communication and challenging behavior in young children with autism spectrum disorder (ASD), and caregiver adherence to programs has predicted child outcomes (Strauss et al., 2012). Recent reviews have summarized the literature on caregiver training interventions based on the principles of behavior analysis, but none have assessed the quality of intervention studies. This review evaluated 35 studies (22 single-case and 13 group design studies) published between 1991 and 2021 using descriptive analysis and the Council for Exceptional Children (CEC) quality indicators. Only seven of the studies reviewed met all quality indicators, as most studies did not meet standards regarding the reporting of internal validity or outcome measures and dependent variables. Nearly all studies within the review reported positive outcomes for caregivers or children following intervention, but these results are questionable given the limitations in meeting and reporting quality indicators. Future studies should ensure that the prescribed indicators are met when developing, conducting, and reporting research to increase confidence in their results.