This study aims to (1) produce an instrument for measuring college student entrepreneurial skills; (2) describe the quality of the measurement instrument for college students' entrepreneurial skills; (3) describe the practicality of the measurement instrument for college students' entrepreneurial skills. The method used in this study is the development of the Retnawati procedure (2017). The steps in this research are instrument planning, instrument testing, and measurement. This research was conducted at four universities in Yogyakarta, Indonesia. With the number of respondents as many as 300 college students. The characteristics of the assessment instrument developed were based on content validity, construct validity, and the reliability and practicality of using the instrument. Content validity uses expert judgment with the Aiken V formula and is calculated using Ms. Excel. Construct validity was carried out using two methods, namely EFA and CFA. Reliability using Cronbach's Alpha formula. The results showed that (1) the college student's entrepreneurial skills measurement instrument has five aspects, namely technopreneur, ecopreneur, sociopreneur, edupreneur, and entrepreneur management that will be developed; (2) the quality of the instrument was tested well by using two approaches, namely content and construct validity; The test results of the content validity instrument > 0.7 so that the results of the validity test are declared valid. Construct validity, the result of KMO value is 0.960 > 0.05. Criteria for the model fit test (good of fit) because the p-value is 0.16722 (p 0.05), the RMSEA is 0.016 (RMSEA). 0.08). Reliability 0.919 ([greater than or equal to] 0.7); (3) practicality in developing the instrument has a very practical value in terms of clarity of instructions, use of instruments, clarity of sentences/language, adequacy of time, skills to be measured, and clarity of scoring instructions. Instruments practically test show 85% very practical, 11% practical, 3% quite practical, 1% impractical, and 0% very impractical category.