Information and communication technology (ICT) became an alternative approach to tackle the challenges rising of COVID-19 pandemic. Online learning depends on availability of internet, suitable infrastructure, learning management systems (LMSs) and the effective educational policies. This research aims to investigate e-learning factors in integration of ICT in higher education in Thamar University, Yemen. Sample of 264 participants including faculty members, administrative staff and students of Thamar University was selected to answer the questionnaires. Quantitative approach was conducted to analyse collected data by using SPSS. Results of this research revealed that ICT elements including internet, infrastructure and LMS have positive ad significant role in integration of ICT in higher education in Thamar University while the educational institutions' policies play negative and insignificant role. The results also revealed the lack of universities and government's support to facilitate e-learning during COVID-19 and suggested for more fund and training for stockholders in education.