Decolonization has multiple meanings and interpretations which reflect not necessarily the arbitrariness of the concept but the complex history of colonialism and the struggles that colonized people have endeavoured to carry on. The level of oppression and subjugation may vary, but there is hardly any one living in the global South (i.e., marginalized communities of both developed and developing countries around the world) who are not affected by colonialism. In the last few years, coloniality and its effects on education are critiqued by scholarly community. In this paper, with an in-depth exploration of the colonial history of Canada, I explore how the epistemologies of the global South were colonized, what decolonization efforts are made by indigenous scholars, and what challenges remain ahead.