Charter school policies have focused on improving three aspects of schools--autonomy, innovation, and accountability--with the intention of promoting advances in curriculum, instruction, and learning that lead to better student outcomes. However, most research on charter schools tends to neglect school organizational and instructional conditions. Overall, reviews show that charter schools have inconsistent effects on student achievement scores, a finding that masks heterogeneous effects among different types of charter schools, operators of charter schools, and authorizers of charter schools and the organizational and instructional conditions under which they operate. This systematic review of the literature focuses on what we know about the organization of charter schools and the resources--material, human, and social as well as professional development and teaching practices--within them. We end by identifying gaps where more research is needed.