This study sought to investigate the impact of COVID-19-induced flexible work arrangements (FWAs) on gender differences in research outputs during COVID-19. A mixed research methodology was used, focusing on higher learning institutions in Zimbabwe. Purposive sampling was applied to select 250 researchers from the 21 registered universities in Zimbabwe. The study's findings revealed that institutions of higher learning in Zimbabwe did not provide the necessary affordances to enable both male and female academics to work from home effectively. The study also established that FWAs were preferred and appreciated by both male and female academics. However, whilst both male and female academics performed their teaching responsibilities without incident, unlike males, females struggled to find time for research, thus affecting professional growth and development negatively for female academics. Cultural traditions were found to subordinate females to domestic and caregiving responsibilities unrelated to their professions. The findings raise questions on the feasibility of the much-recommended FWAs for future work on female academics' research careers. Thus, without the necessary systems and processes to support female researchers, FWAs can only widen the gender gap in research outputs. This study contributes to the Zimbabwean higher learning institutions' perspective on how FWAs' policies and practices could be re-configured to assist female researchers in enhancing their research outputs as well as their career growth.