Currently, museums seek to improve education and inclusion through the use of technology, and it is essential to value the didactic and technological advances through the use of new tools (ICT), at an intercultural and intergenerational level, adapting the exhibition messages to the diversity of the public, with a special interest in disability. Therefore, we have conducted a systematic review with a selection of 511 examined articles covering 2005 to 2020. Ten databases have been used in the exhaustive search and selection: 1Findr, Semantic Scholar, Scopus, Google Scholar, Microsoft Academi Search, Wos, Dialnet, Miar, Circ, Eric. The objective is to show the current elements for the development of cultural access favouring inclusion and participation avoiding exclusion. Among the conclusions obtained, it is evident that there is a need for greater knowledge on the part of the didactic teams, it is necessary to connect with the public with inclusive participative actions both in the museum and in the digital environment, providing the appropriate tools to encourage debate and critical thinking. It is necessary for professionals to collaborate between institutions, in order to achieve significant progress in awareness, education and real access to all audiences.