At a public university in March 2020, 234 students (78% female; 63% second year, 28% third year) enrolled in a psychological statistics course described their experiences during the first week of the transition to remote instruction in response to coronavirus disease 2019. Qualitative responses indicated 13 common concerns in the following domains: financial, housing, and food security; social life; emotional health; sleep; and academic performance. Students with lower socioeconomic status were more likely to experience financial instability, food insecurity, and academic challenges.