Purpose: The current study aims to explain the relationship between entrepreneurial education and entrepreneurial intention through a moderated mediation model from the lens of social cognitive career theory (SCCT). Specifically, two main objectives of this study are (1) to explore the mediation role of entrepreneurial self-efficacy in the relationship between entrepreneurial education and start-up intention and (2) to investigate the moderate role of family support on the effect of entrepreneurial education on entrepreneurial intention. Design/methodology/approach: This study uses a sample of 1879 students in Vietnam and SPSS PROCESS macro developed by Hayes (2012) to examine the indirect effect of entrepreneurial education on start-up intention via entrepreneurial self-efficacy and the moderated mediation effect of family support. Findings: This study reveals that the association between entrepreneurial education and entrepreneurial intention is partially mediated via entrepreneurial self-efficacy. Also, the effect of entrepreneurial education on entrepreneurial self-efficacy and start-up intention was negatively moderated by family support. Furthermore, the indirect effect of entrepreneurial education on intention to form a venture via entrepreneurial self-efficacy is also negatively moderated by family support. Originality/value: The entrepreneurial education and start-up intention linkage remain a significant gap in the entrepreneurship literature. Therefore, this research study is expected to contribute to clarifying this linkage by utilizing the SCCT to explain how entrepreneurial education contributes to entrepreneurial intention.