Background: In the context of recent research in science education and continued struggles to understand how best to support science teachers, epistemological frames, made up of sets of epistemological resources teachers activate, have emerged as an important focus of research. However, at the time of this writing no research was available to identify the epistemological frames activated by preservice science teachers (PSTs). Methods: In this research, using qualitative research methods, we studied and applied a coding scheme to identify 10 PSTs' epistemological framing in their early teaching as part of a science teaching methods course. Three observations and three interviews of each PST served as primary data sources. Findings: We found three main epistemological frames activated. Further, we identified the contexts in which these frames were activated, where contexts can be understood as situations characterized by different possible dimensions within which resources are activated. We also described dynamics noted by PSTs related to the activation of specific epistemological resources and identified frames. Contribution: This research is a relatively new application of the epistemological framing framework that has potential to help science teacher educators better understand and support PST learning and practice.