Cultures could influence parents in the way they perceive adverse situations and in how external factors influence resilience, which in turn, may differentially affect the quality of life of a child. The present study aimed to examine the associations between different dimensions of parental resilience and the quality of life of children in Indonesia. The samples consisted of 497 families. This study used the Parenting Resilience Elements and the Quality of Life Questionnaire. Parental resilience consists of three dimensions, knowledge of child's characteristics, positive perception of parenting, and perceived social support. Knowledge of child's characteristics, one of the parental resilience dimensions, significantly related to the Quality of Life dimensions of communication and influence, and development. Positive perceptions of parenting related to socio-emotional well-being. Perceived social support related to material well-being, activity, and socio-emotional well-being. We found that the parental resilience related to Quality of Life of children with developmental disabilities. Some findings could be unique for a collectivist culture and highlight the complexities of the association between different factors of parent resilience and Quality of Life of children with developmental disabilities in Indonesia.