Integrating technology in k-12 classrooms is still a challenge. However, the International Society for Technology in Education (ISTE) provides standards that can help educators to integrate technology in teaching and learning. The purpose of this study is to share the pillars of the ISTE Standards for Educators that in-service teachers felt comfortable and confident to use in their classrooms. This study used a systematic review to examine the primary research publications on the experience of in-service teachers using ISTE Standards for Educators as a framework or a foundation to create an instrument. The findings showed that the in-service teachers had focused on the pillars of Designer, Analyst, Facilitator, Citizen, and Learner in their teaching and learning activities. These five pillars may serve as a foundation for in-service teachers to fully implement the seven pillars of ISTE Standards for Educators in the classrooms. The authors also recommend the instructors at a postsecondary level to use the ISTE Standards for Educators in their teaching and learning activities.