Rural schools in the United States serve more than 9.3 million students (Showalter et al., 2019), often possessing strengths and facing challenges that differ from their metropolitan and suburban counterparts. To attend to the unique context of rural schools and to encourage rural education research in key areas, the National Rural Education Association's (NREA) Research and Higher Education Committee presents the "National Rural Education Association Research Agenda--2022-2027." The central goal of this agenda is to present major priorities for current and future rural education research in order to support the efforts of rural education practitioners, administrators, and school board members as well as advise the policymakers, community leaders and activists, nonprofit organizations, and funding organizations who contribute to the vitality of rural schools and communities. A comprehensive research project that utilized surveys, interviews, and focus groups guided the direction of the agenda, from which spatial and educational equity emerged as the most common theme.