The Canadian Agility and Movement Skill Assessment (CAMSA) is a circuit-based measure of motor competence. This study aimed to investigate the validity and reliability of CAMSA in Spanish children. A sample of 749 children participated voluntarily. Acceptable-to-good internal consistency ([alpha] = 0.54 and G-coefficient = 0.88) and moderate-to-excellent inter- (ICC: 0.83 to 1.00), intra-rater (ICC: 0.99 to 1.00) and test-retest reliability (ICC: 0.70 to 0.83) was found in convenience subsamples (n = 84 observers' reliability; n = 69 test-retest). Concurrent validity was moderate (CAMSA score with "Körperkoordinationstest für Kinder": r = 0.45; n = 90). Confirmatory factor analysis supported the one-factor model (CFI = 0.95; RMSEA = 0.02; SRMR = 0.02). Boys had higher scores than girls and older-children had higher scores than younger-children. The CAMSA can be used as a valid and reliable instrument for assessing motor competence in Spanish children.