Recognizing the renewed national awareness of racial tensions and economic disparities, the need for solace in the wake of the coronavirus pandemic, and the legacy of the events of September 11, 2001, American art museums have unique opportunities to provide safe spaces in which to encourage mutual respect through interfaith dialogue. This case study highlights the important role that museums can play in exploring diverse points of view and in inspiring empathy and religious understanding. The authors examine the mutual benefits of bringing together museum staff, academics, faith and community leaders, and docents of various faiths, with each contributing their own expertise to the process. This article considers the opportunities and criteria for selecting artworks that effectively present recurring themes of shared fundamental beliefs across history and cultures, and introduces an innovative touring model that promotes open and respectful discourse and our common humanity.