It is not new for mother-scholars to face challenges in balancing work and life demands; however, the COVID-19 pandemic has redefined the meaning of mother-scholars as they maneuver working from home, caring for their dependents, and maintaining their research productivity. The following manuscript is a collection of autoethnographic studies of the experiences of four women of differing ranks in the academy: pre-tenure, mid-career, and late-career. What they all have in common is caregiving responsibilities that abruptly derailed their research agendas when the pandemic interrupted their lives.