In the aftermath of the acute phases of COVID-19, some schools are adopting trauma-informed, high-leverage practices to help educators and students cope with the psychological impact of the pandemic on learning. Given the scope of the pandemic's devastation, scattershot approaches are not enough. A systemic approach is needed to ensure that all educators and students can benefit from trauma-informed approaches. East Tennessee State University and Unicoi County Schools recognized the value of developing and sustaining a partnership to build strategies and leadership capacity for trauma-informed systems. Seeing the need for professional learning, coaching, and assessment tools, the professors and researchers at the Strong Brain Institute and Educational Leadership and Policy Analysis Department developed a five-year strategic partnership with the school district to design a pre-K-12 resilient schools district model so students will receive a continuum of services through elementary, middle, and high school transitions. This article discusses how the trauma-informed system highlights social and emotional learning and resilience and how they are connected to academic excellence and college and career opportunities.