This project focused on integrating an international component into the one-semester biochemistry course, a required course for biology, chemistry, and forensic science majors at the institution. A driving question was how to integrate the international component into the course while showing direct relevance to the course and students' lives. Therefore, it was decided to use global health as a focus. Students were required to analyze current or historic events or issues of global significance with direct or indirect impacts on health. In addition, a specific component required students to make connections to the course content and its relevance to biochemistry and their career interests. Student learning outcomes for the project are that students will be able to a) demonstrate knowledge of course concepts and how they apply to global health, b) evaluate and compare the forces shaping global issues, both now and in the past, and c) compare and contrast global events/issues and impacts internationally and domestically. The process of course revision and implementation, and outcomes are described.