Nurses are expected to provide culturally competent care. Many health care organizations support the need for more emphasis on cultural competency in nursing academia. Institutions of higher education have begun encouraging more course internationalization and globalization to help accomplish this goal. The purpose of the current article is to describe the steps involved in the internationalization of NURS 3630: Conceptual Basis of Professional Nursing course at Albany State University. This course is a part of the required courses within the Darton College of Health Professions Post-Licensure Registered Nursing program and was purposefully selected for internationalization. Conversations between nursing faculty, the Office for International Education, and nursing leaders occurred in the decision-making process. Course objectives and assignments were recreated or altered to have a more cultural and global focus. Four student learning outcomes were addressed in the internationalized course. Positive student feedback regarding course information learned and usefulness was received at the end of the semester. Future suggestions for the course include integrating culture grading rubrics, pretest and posttest administration, faculty professional development, course design team collaboration, and student input.