The goal of the present study was to assess the family quality of life (FQOL) in families with children with developmental disabilities in Bosnia and Herzegovina. We examined the FQOL in relation to parents' demographic variables (gender, age, employment status), children's gender and age, type of children's disability (mild and moderate intellectual disability, autism spectrum disorder) and parent's depression, anxiety, and stress levels. The sample consisted of 270 parents of children with disabilities; 90 parents of children with autism spectrum disorder, 90 parents of children with mild intellectual disability, and 90 parents of children with moderate intellectual disability. We also included a control group of 90 parents of typically developing children. The results of this study showed that parents of children with autism spectrum disorder and parents of children with moderate intellectual disability had statistically significantly lower FQOL than parents of children with mild intellectual disability and parents of typically developing children. Child's gender had a significant effect on FQOL. Also, depression, anxiety and stress levels significantly affected FQOL, while the parents' gender, age, and employment status did not have a significant effect. Implications of these findings are discussed and some measures on supporting parents are proposed.