Background: The higher education institutions will go a major innovation, reform, and change to achieve the goal of achieving quality, accreditation, and autonomy. Purpose: To evolve a holistic framework and strategies for achieving, quality, accreditation, and autonomy. Methods: The study is an exploratory qualitative study. The unstructured questionnaire is used for conducting the research which is responded to by 754 respondents working in higher and technical education institutions in the country. Result: The framework suggested in this study is having four rings. The innermost ring is a governing ring that is responsible for the professional governance of the institute with the help of the governing teams. The second ring is the capacity-building ring which is responsible for capacity building and capacity development and creating an innovative climate and culture. The third ring is a functional ring that is responsible for implementing the innovations, reforms, and change in the institute that are aligned to the provisions of the national education policy 2020. The fourth ring is the product and service ring and also the outermost ring which is responsible for the interface between the institution and the external environment. Conclusion: The reform-oriented institutions are provided strengths by these four rings to obtain accreditation and autonomy and sustain it. The strategies for each ring are suggested in the context of the National Education Policy 2020. It is suggested to implement the framework and strategies to effectively, efficiently, and productively implement the innovations in the institute.