This study examined the differences between the responses of federal and state universities on entrepreneurial skills required for business education graduates' employability in Cross River State. Specifically, the study examined the difference between the responses of federal universities and state universities on planning skills, marketing skills and management skills on the business education graduates' employability in Cross River State, Nigeria. The population of this study consists of 2,575 business education students in the two public universities in Calabar. The sample of this study consists of 256 business education students drawn from the department of business education of the two public universities in Calabar, representing 10% of the total population. The results of the analysis revealed that there is no significant difference between students of the two universities. Findings also revealed that there is significant difference between students of the two universities on marketing skills and business management skills for business education graduates' employability in Cross River State. Based on the findings of the study, it was recommended among others that teachers should include activities that will enhance planning skills of students.