Biochemistry encompasses a broad range of life science disciplines. Unlike more vocational disciplines such as pharmacy or medicine, the career path associated with biochemistry is less clearly defined. An important question is whether the skills set provided by post-graduate biochemistry education, defined as BSc (Hons.), MSc, or PhD degrees, is aligned with the requirements of a career in academia or industry. This article reports on former post-graduate biochemistry students and their careers and aims to establish whether former post-graduate students perceive a post-graduate qualification in biochemistry as useful for entry into the job market. This article is based on responses of 64 former post-graduate biochemistry students from South African universities who have graduated between 2010 and 2019. Findings show that most post-graduate biochemistry graduates continue a career in academia after graduating. Some pursue a career in the industry, while a very small number of biochemistry post-graduates are currently unemployed. These findings suggest that a post-graduate degree in biochemistry provides the necessary scientific and research skills sought after by the employment sector in South Africa.