This study examines the psychosocial hazards experienced by academic staff working in UK institutions over time. A risk assessment framework developed by the Health and Safety Executive (HSE) was used to measure seven key hazards: demands, control, support from managers and colleagues, relationships, role and change management. Data were obtained from three waves of a national survey of academic staff across the UK (2008, n = 6,203; 2012, n = 7,068; 2014, n = 3,952). Mean scores for each hazard were compared with HSE benchmarks from the UK working population and changes over the three waves were examined. Apart from job control, none of the benchmarks was met and the risk associated with demands, manager and peer support, role and change was particularly high. An increase in most of the psychosocial hazards was found over time, particularly for job demands, control, role and relationships, showing clear cause for concern. How the findings could be used to monitor the wellbeing of academic staff over time and develop targeted interventions is considered.