Purpose: This study aims to develop a new entrepreneurial university model that will provide a comprehensive picture and explain how universities can become entrepreneurial by considering several factors, both internal and external. Design/methodology/approach: This research collected data by conducting a survey and elaborates on the judgments of informants who are experts in their fields. The gathered data were analyzed with the ISM method and MICMAC analysis. Findings: This study identifies key factors of entrepreneurial university transformation, specifically, five key success factors and one constraint factor. Research limitations/implications: This study has limitations in terms of its in conducting interview techniques. Data collection, which should be maximized in producing agreement through focus group discussions, can more acutely identify factors through consensus. Practical implications: This study provides an overview of how universities may transform, following a path to become entrepreneurial by paying attention to the factors driving this transformation. The model demonstrates that while the university plays a central role, the participation of other parties within the ecosystem is also important. Originality/value: This modeling technique deconstructs a complex system into several sub-systems, so that it can be studied in greater depth. Using ISM and MICMAC, a hard system methodology, this study advances a different and more comprehensive model.