Children with autism spectrum disorder (ASD) who have problems such as inactivity and the lack of communication need interventions that enable them to participate in society just like their peers. The purpose of this study was to investigate 'I can have physical literacy' programme (ICPL) on physical literacy (PL) in children with ASD. This study was a quasi-experimental study with the pre-test, post-test design, and control group. The intervention programme was based on ICPL and the Canadian assessment of physical literacy (CAPL). The results showed that physical competence (p=0.005), daily behaviour (p=0.003), motivation and confidence (p=0.005), knowledge (p=0.001), and PL (p=0.005). The intervention is based on the PL effect on physical competence to engage in physical activity (PA), and also embraces more than the body and development of physical skills which includes other factors.