The Open Distance Learning (ODL) commenced in Nigeria in the year 2003 by the National Open University of Nigeria (NOUN) and many universities in the country have also adopted it. The study focused purposely on four ODL centers in Kwara state. Five research questions and three research hypotheses were formulated. The student samples were selected through convenience sampling method. Two research instruments designed by the researchers for data collection were subjected to both face and content validity. The questionnaire was pilot-tested using Cronbach Alpha test which yielded 0.67 coefficient of reliability. The hypotheses were tested using chi-square analysis and research questions were answered using percentages. Findings revealed a significant relationship between ODL programs efficiency and resources availability (p 0.00 < 0.05), significant relationship between ODL program and academic learner support facilities (p 0.00< 0.05). The study concluded that teaching and learning resources availability and usage have significant influence on the efficiency of ODL programs. It is therefore recommended that learning resources within the reach of learners should be in use at the centers and support facilities should be improved upon by adopting more widely used media to communicate with students.