Delays in social and communication skills are associated with autism spectrum disorder (ASD). Structured play groups (SPGs) was deemed an evidence-based practice (EBP) for children with ASD. A critical review of research published within the past 16 years and accessible in four databases was conducted with a total of 3,153 articles identified of which 15 were determined to have met inclusion criteria. A total of 163 participants from 3 to 12 years of age were reported on within the articles evaluated. Of the 15 articles, 12 implemented a single-subject design and 14 of the 15 interventions were implemented within the natural settings of the participants. Findings provide a fuller understanding of the efficacy of SPGs for children with ASD. Additionally, this review demonstrates positive results in a variety of settings, as well as an in-depth evaluation of the inclusion and training of the typically developing peers.