ERIC Number: EJ1327186
Record Type: Journal
Publication Date: 2022-Mar
Pages: 12
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0162-3257
EISSN: N/A
The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder
DeMayo, Marilena M.; Pokorski, Izabella; Song, Yun J. C.; Thapa, Rinku; Patel, Shrujna; Ambarchi, Zahava; Soligo, Domenic; Sadeli, Indra; Thomas, Emma E.; Hickie, Ian B.; Guastella, Adam J.
Journal of Autism and Developmental Disorders, v52 n3 p1211-1222 Mar 2022
There is an increasing interest in using magnetic resonance imaging (MRI) as a tool for precision medicine in autism spectrum disorder (ASD). This study investigated the feasibility of MRI scanning in a large comprehensive, inclusive and test heavy clinical trial for children (aged 3-12 years) with ASD, without functioning constraints for participation. Of the 71 participants enrolled who consented to the MRI, 24 participants (38%) successfully completed an MRI scan at baseline along with other assessments. This scanning followed a familiarization procedure at two preceding visits. At post-treatment, 21 participants successfully completed the MRI scan. This study highlights the challenge of completing MRI assessments in ASD populations when conducted as one of a number of tests in a clinical trial.
Descriptors: Diagnostic Tests, Brain, Medicine, Autism, Pervasive Developmental Disorders, Children, Outcomes of Treatment, Clinical Diagnosis
Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://bibliotheek.ehb.be:2123/
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A