This study examined the relations among family socialization, loneliness, linguistic skills, and reading comprehension in 78 Mandarin-speaking Chinese third graders with a mean age of 8.67 years old. The participants were administered a battery of tasks to assess their non-verbal intelligence, linguistic-skills, word reading, and Chinese reading comprehension, and asked to complete loneliness, trait anxiety, family socialization, and demographic questionnaires. Regression analysis showed that family socialization, loneliness, and linguistic-skills were significant predictors of reading comprehension after controlling for SES, non-verbal intelligence, trait anxiety, and word reading. Mediation analysis showed that linguistic skills fully mediated the relation between loneliness and reading comprehension after accounting for the variance of controlled variables. These findings suggest that family socialization and loneliness significantly affect the development of reading comprehension.